Differential correlations between changes to glutathione redox state, protein ubiquitination, and stress-inducible HSPA chaperone expression after different types of oxidative stress
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چکیده
منابع مشابه
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There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species and mitochondrial dysfunction. Here, we review the evidence for a disturbance of glutathione homeostasis that may either lead to or result from o...
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Redosis evoked in different tissues by methylene-blue or menadione (oxidants), resulted in an increase in heart frequency, while oxidosis evoked by thiamine or cysteine (reductants) diminished the frequency. In isolated organ tissues where compensatory redox feed back overshoots are rarely to develop, owing to the low redox buffer capacity and lack of the influence of nervous and humoral factor...
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Cells are sensitive to a variety of signals in their environment, which they respond to and integrate. Signal transduction at the cellular level refers to the movement of signals from outside the cell to inside. A "cross-talk" between heterologous cell signaling systems gives a complex communication of molecules in various tissues a new dimension and specifies the type of the obtained biologica...
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ژورنال
عنوان ژورنال: Cell Stress and Chaperones
سال: 2018
ISSN: 1355-8145,1466-1268
DOI: 10.1007/s12192-018-0909-y